What are your thoughts on giving RhoGam at 28 weeks pregnancy?
My go-to website for reliable health information is MedLine Plus, the consumer health website run by the U.S. government. When I searched it using the terms "Rh incompatibility" it came up with this. I didn't check out the links, but I would predict that they will have the same drawback as in my original response, namely that there is no info on adverse effects. The standard for making an informed decision is to have both. Still, I have never heard or read anywhere that Rhogam has had adverse effects, and I think it would have stuck in my mind if I had.
As I understand it, Rhogam works by diminishing the mother's immune response and therefore preventing her body from producing antibodies to the foreign blood antigen. Considering this, there must be a consequence of routinely using the drug. Maybe the negative effects are minute or do not have clinical significance, but I am still weary of it's use during a normal pregnancy when the chances of the maternal and fetal blood mixing are extremely small.